Childhood epilepsy surgery ‘prevents cognitive deterioration’

Posted Mar 4 2014 in other treatments for epilepsy

entorhinalm

Drug-resistant epilepsies caused by brain tumours should be treated with surgery as soon as possible to prevent cognitive deterioration, according to a new study.

The report, which was published in the February edition of Neurosurgery, took the form of a retrospective review of 29 paediatric patients who underwent surgical resection between 2000 and 2011.

At their final follow-up, some 76 per cent of subjects were seizure-free, with 62 per cent weaned off antiepileptic drugs.

More importantly, researchers found surgery tended to be followed by improvements to cognitive functioning, including verbal IQ, performance IQ and visual memory, as well as a trend towards full-scale IQ gains.

None of the subjects experienced cognitive deterioration as a result of their surgery. Contrastingly, untreated glioneuronal tumours are associated with a long-term decline in cognitive functioning.

Completeness of resection predisposes to favorable outcomes regarding seizure alleviation,” the researchers commented. “Surgery is linked to improvement rather than to deterioration on a group level.”

Posted by Bob Jones