A new study has highlighted for improved awareness of sudden unexpected death in epilepsy in order to encourage better understanding and management of the condition.
Below are the most recent news stories about epilepsy from Epilepsy Research UK and from around the world. You can choose different categories from the side bar on the left (for details of grants made prior to 2012, please visit our research portfolio). You can also catch up with Epilepsy Research UK's fundraising and research news in our supporter newsletters.
If you wish to receive articles written by Epilepsy Research UK about specially selected research developments, please register for our e-newsletter. This will automatically arrive in your inbox each month.
A new type of ultra-thin microelectrode has shown the potential to revolutionise imaging of the brain, opening the door for new epilepsy research innovations.
Background Carbamazepine is a widely used anti-epileptic drug, which is usually well tolerated with only mild side effects. In rare cases, however, it can cause a severe, blistering (and sometimes fatal) skin condition, but there is no way of predicting who will have this reaction. In 2011, Epilepsy Research UK awarded Dr Ana Alfirevic and colleagues, at the University of read more
Scientists in the US and Europe have linked several new genes to epileptic encephalopathies. This is the largest collaborative study of its kind to date, and it could lead to the development of new treatments. Background Epileptic encephalopathies (EEs) are severe, difficult-to-treat childhood epilepsy syndromes, characterised by aggressive seizures (often of multiple types); developmental delay and learning and behavioural read more
A new study has demonstrated the common memory problems that can often accompany cases of childhood epilepsy.
A new robotic device that can be used to perform brain surgery through the cheek could greatly aid the future treatment of epilepsy.
New US research into the function of neurons could potentially pave the way for new insights into brain disorders, including epilepsy.
A new study has suggested that scans of the frontolimbic brain network could be a useful means of predicting depressive symptoms in temporal lobe epilepsy. Research from the University of California, San Diego has been published in the medical journal Epilepsy Research observing that frontolimbic functional connectivity demonstrates a strong correlation with depressive symptoms. By assessing data from 21 patients read more
Single episodes of juvenile status epilepticus can help to reduce the threshold to adult seizures in various ways, according to new research. Carried out by the University of Ioannina in Greece, the study built on previous findings suggesting that status epilepticus episodes in immature rats can induce a long-term increase in cholinergic excitation, a process that can increase seizure risk. read more
A new model for predicting seizures in critically ill children has demonstrated its potential efficacy in a study.
US scientists have developed an innovative new method to study epilepsy in samples of patients’ brain tissue.
A new study has highlighted a potentially higher risk of venous thromboembolisms among patients with epilepsy. The research from the Medical University of South Carolina examined all inpatient, emergency department and hospital-based outpatient encounters in South Carolina from 2000 to 2011 to monitor the possible correlation between the two conditions. A total of 138,497 people with migraines and 67,900 people read more
A new study has highlighted the potentially positive outcomes that refractory epilepsy patients can achieve even after being rejected for surgical treatment. Carried out at the Assaf Harofeh Medical Center in Israel, the research looked at the outcomes of patients rejected from focal resective surgery due to medical reasons, or who simply chose not to undergo it. It examined 52 read more
A new study in the US will aim to shed light on the process leading from initial seizures to the onset of epilepsy later in life.
Gene mutations associated with severe and difficult-to-treat forms of childhood epilepsy have been identified by an international team.
The severity of comorbid psychiatric symptoms in epilepsy clinics could be reduced using a colocation model, according to a new study. Conducted at the Cheyenne Regional Medical Center and Dartmouth-Hitchcock Medical Center in the US, the research aimed to assess the potential impact of colocated psychiatric services within outpatient epilepsy clinics – a previously under-reported consideration. According to data published read more
A US study has illustrated the mental health benefits that cognitive behavioural therapy (CBT) can offer to adolescents with epilepsy. Conducted by the University of Michigan and published in the medical journal Epilepsy & Behavior, the research saw 34 adolescents enrolled in a CBT programme to see if it would enhance their psychosocial functioning. CBT is a talking therapy that read more
Researchers have highlighted the potentially beneficial role that levetiracetam can play in reducing abnormal network activation in temporal lobe epilepsy patients. The University College London study used functional MRI and a model of working memory analysis to investigate the effects of levetiracetam on cognitive network activations in patients with drug-resistant forms of temporal lobe epilepsy. Looking at data from more read more
A major new collaborative international study has shed light on new genes identified with the development of severe childhood epilepsies. The project saw members of the European EuroEPINOMICS consortium analyse the genetic information of 356 patients and their parents, looking for genes that had acquired new mutations in children with severe epilepsies when compared to the DNA of the parents. read more
Pre-hospital guidelines for seizure emergencies in the UK are in need of an update, according to a new study.