People who have lived with temporal lobe epilepsy for only a short time might achieve better post-surgical outcomes than those with longer disease durations, according to a new study. Published in Arquivos de Neuro-Psiquiatria – the official journal of the Brazilian Academy of Neurology – the research aimed to investigate the influence of a patient’s age and seizure onset on read more
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Adolescents with epilepsy are more likely to experience seizures in public places if they are affected by high levels of anxiety and depression. This is according to a study published in the Brazilian Academy of Neurology’s Arquivos de Neuro-Psiquiatria, which assessed depression and anxiety symptoms among adolescents with epilepsy compared with those without epilepsy. A total of 50 subjects attending read more
A new study has shed light on the various factors affecting the development of patient-reported cognitive side effects of antiepileptic drugs.
Specific gene mutations existing only in the brain have been identified as possible causes of intractable epilepsy.
A new study has shed light on potential clinical or electroencephalographic (EEG) features associated with hard-to-treat cases of benign childhood epilepsy with centrotemporal spikes (BCECTS). Carried out by Sichuan University in China and published in the Journal of Child Neurology, the study looked at a total of 87 children with typical BCECTS, who were divided into two groups: patients whose read more
A new study has shed light on some of the internal and external factors affecting the employment status of people with epilepsy.
Background Epilepsy susceptibility genes, which don’t necessarily cause epilepsy but render a person more likely to develop it if exposed to certain triggers, are of great interest in research. Whilst adult rodents have long been useful for genetic studies, they are only used when absolutely necessary, and scientists are keen to employ simpler model organisms that have less capacity to read more
A new study has cast light on the elevated risk of low sodium levels among elderly post-stroke seizure patients treated with eslicarbazepine acetate (ESL). Published in the medical journal Seizure, the two-year observational study examined the use of ESL in individuals with new-onset post-stroke seizures. The patients were followed up for seizure control and side effects, including serum sodium on read more
German scientists have made a potentially important discovery relating to the development of temporal lobe epilepsy.
European epilepsy monitoring units need to implement a more standardised model of dealing with adverse effects among epilepsy patients, according to a new study.
Certain types of early-onset epilepsy are caused by previously unknown mutations of a potassium channel gene called KCNA2, according to a new study.
Direct brain neurostimulation can provide long-term benefits for people affected by partial-onset seizures, according to a new study.
Misconceptions about epilepsy surgery could be leading to the treatment technique being underutilised, according to a new study.
A new study has shed light on the persistent issue of injuries from seizures among childhood-onset epilepsy patients.
A new study has shed further light on the link between social deprivation and a higher risk of epilepsy.
A new study has demonstrated the effectiveness of the drug perampanel in the treatment of a paediatric population with refractory epilepsies. Researchers from Germany, Austria and Denmark carried out an observational, retrospective survey in collaboration with multiple centres in Europe to report the first clinical experiences concerning effectiveness and tolerability of perampanel in this patient population. The study population consisted read more
A new self-management intervention programme targeting cognitive dysfunction could help to improve quality of life and reduce memory-related disability in adults with epilepsy, according to a study. Carried out by the Dartmouth-Hitchcock Medical Center in the US, the small-scale investigation showed that the programme was feasible for delivery to a rural population with epilepsy, with 13 of the 16 enrolled read more
A new study has underlined the heightened risk of impaired intrauterine growth of foetuses in women with epilepsy.
A new study has highlighted specific structural brain abnormalities associated with benign childhood epilepsy with centrotemporal spikes (BCECTS). Carried out by Asan Medical Center in Seoul, the research analysed surface and volumetric magnetic resonance imaging data of children with newly-diagnosed BCECTS in order to determine the presence of cortical thickness and gray matter volume abnormalities. According to results published in read more
Patients with drug-refractory epilepsy could benefit from reducing the number of antiepileptic drugs (AEDs) they receive, according to a new study. Carried out by the All India Institute of Medical Sciences, the research looked at 962 patients with drug-refractory epilepsy who had been admitted to neurology wards. Modifications in the number and dosage of AEDs were done with a target read more