Children with epilepsy initially perceive stigma associated with the condition at the time of their diagnosis, but this perceived stigma generally decreases over time. This is the conclusion of a new study led by the Cincinnati Children’s Hospital Medical Center, which aimed to assess perceptions of stigma among children newly diagnosed with epilepsy and their caregivers over a two-year period. read more
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A new study has underlined the potential benefits offered by lacosamide, an antiepileptic drug (AED) therapy for the adjunctive treatment of focal-onset seizures. Researchers from Western Infirmary in Glasgow conducted a prospective audit to assess outcomes associated with the AED in everyday clinical practice, with a total of 160 patients being treated with the drug. It was revealed that 35 read more
Manipulating bodily levels of a certain protein has been found to be a potentially effective way of combating Dravet syndrome, a serious form of epilepsy. Scientists from the University of California, San Francisco looked at a mouse model of the severe childhood epilepsy – which is caused by genetic mutations – to see whether reducing levels of the microtubule-associated protein read more
New research from a number of French universities has shed fresh light on the impact that frontal or temporal lobe epilepsy can have on executive function in children. Executive functions are a number of key cognitive processes that generally help connect past experience with present action, including memory, reasoning, problem-solving, planning and execution. Since executive functions are vulnerable in cases read more
US scientists have developed a genetically engineered line of mice that could be used to greatly enhance current understanding of the way epilepsy works.
A new study has indicated the Atkins diet could potentially offer similar effectiveness to the ketogenic diet in terms of aiding the management of childhood epilepsy. Carried out at the Mofid Hospital in Tehran, the clinical trial survey saw 40 children with refractory epilepsy divided into two groups and trialled on both diet types. The ketogenic diet is a high-fat, read more
A new study has offered fresh insight into the best ways of predicting and guiding the best possible outcomes for patients with juvenile myoclonic epilepsy.
A new UK study has highlighted the need for better education among parents about the benefits ketogenic diets can provide for the treatment of epilepsy.
More needs to be done to improve the effectiveness of interventions designed to help children with epilepsy to manage their own conditions.
Background Optogenetics is an experimental technique that uses weakened viruses to incorporate light-sensitive proteins into neurons. These proteins – known as opsins – are usually ion channels, and their role is to transport specific metal ions into and out of neurons, creating an electrical current (in this case known as a photocurrent because it is triggered by light). Opsins can read more
Background When something piques our interest or we are expecting something, unique wave patterns called gamma oscillations pass through our brains. These oscillations are believed to play a role in higher-level functions (although their precise role is not clear), and their disturbance has been seen in epilepsy, schizophrenia, Alzheimer’s disease and autism. Within the brain are billions of cells known read more
Background Ketogenic diet therapies that are high in fat and low in carbohydrate have been used in the treatment of drug-resistant childhood epilepsy for almost a century. Approximately 40% of children show a 50% or more decrease in seizure frequency after three months following the diet, and the most common side effects are gastrointestinal (and are usually addressed with adjustments read more
A new study has highlighted possible approaches to predicting and reducing epilepsy surgery failure in paediatric patients.
A new study has established a predictive risk model that could make it easier to identify medically intractable cases of epilepsy at an early stage.
Reducing brain levels of the protein tau can effectively block the development of a severe form of childhood epilepsy, according to a new study.
Scientists have created a functional 3D tissue that mirrors the make-up of the brain, opening the door for new epilepsy research efforts.
A new study has underlined the potential benefits and risks of rolandic cortex surgery for the treatment of intractable epilepsy.
A new study has demonstrated the clinical utility of using genetic testing as a means of diagnosing paediatric drug-resistant epilepsy.
A new Australian study has underlined the importance of ensuring epilepsy patients and their families are properly engaged and involved in decisions pertaining to the provision of care.
A new study has suggested that electromagnetic stimulation can alter brain patterns in a way that could be beneficial in the treatment of epilepsy.