A new study from Germany has demonstrated the potential benefits that intranasal midazolam can offer in the treatment of presurgical epilepsy. The research, published in the medical journal Epilepsia, evaluated the tolerability and efficacy of the ictal and immediate postictal application of intranasal midazolam in adolescents and adults during video-electroencephalography monitoring. A total of 75 patients were treated with the read more
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A new study from the Netherlands has demonstrated the effectiveness of the ketogenic diet in the treatment of children with refractory epilepsy. The trial aimed to evaluate the efficacy of ketogenic dietary treatment, and to search for child- or diet-related factors that can predict its effectiveness after 12 months follow-up. In addition, the team wished to determine the usefulness of read more
US researchers have identified several psychosocial predictors that can help to forecast whether or not youths with newly-diagnosed epilepsy will successfully adhere to treatment. The Cincinnati Children’s Hospital Medical Center aimed to find modifiable behavioural predictors of two-year antiepileptic drug (AED) adherence trajectories among young people with epilepsy, controlling for known demographic and medical factors. It is well established that read more
A new study has identified a number of potentially useful behavioural predictors of medication adherence trajectories among youths with newly-diagnosed epilepsy.
A new study has offered fresh confirmation of the equivalent performance that the generic version of lamotrigine, an antiepileptic drug (AED), can provide when compared to the original branded version. Led by the University of Maryland, the study aimed to test the pharmacokinetic performance of both versions in ‘generic-brittle’ patients with epilepsy – those who previously showed sensitivity when switching read more
A new review of existing clinical evidence has provided a clearer insight into the risk of adverse events associated with the antiepileptic drug (AED) levetiracetam. In total, 26 studies with 2,832 patients were included in the University of Perugia-led analysis, which appeared in the medical journal Seizure. The meta-analysis included all available double-blind, randomised placebo-controlled trials performed in any age, read more
A new systematic review of existing evidence has demonstrated the potential benefits of intravenous lidocaine as a means of controlling status epilepticus (SE) and refractory status epilepticus (RSE). For this new study, published in the medical journal Seizure, 13 studies involving 76 adult patients were assessed. The cohort experienced 82 episodes of SE/RSE, with patients receiving a number of different read more
Adults with epilepsy are more likely to experience social anxiety, with this impact also felt by their close family members, according to a new study. Carried out by Baskent University in Turkey, the research looked at anxiety, depression and social fear and avoidance levels in 48 adult patients with epilepsy and 48 first-degree cohabiting family members, compared to 43 controls. read more
A new study has highlighted the impact of epilepsy and antiepileptic drugs (AEDs) on the metabolic profile in adults with autism spectrum disorder and intellectual disabilities. The Israeli study, published in the journal International Clinical Psychopharmacology, aimed to investigate how epilepsy and AEDs affect body mass index (BMI), fasting blood glucose (FBG) and total cholesterol of individuals in this demographic. read more
The discovery of a part of the brain that plays a key role in controlling breathing has provided a new insight into sudden unexpected death in epilepsy.
A 15-year study has demonstrated the benefits vagus nerve stimulation therapy can provide for patients with treatment-resistant epilepsy.
A French study has highlighted the need for more attention to be paid to the risk of falls in older people with epilepsy. The small-scale research project followed four women of a mean age of 84.5 years affected by a number of forms of epilepsy, with falls associated with physical seizures or a loss of consciousness. According to data published read more
A new study has demonstrated the efficacy of lacosamide as an initial add-on therapy for epilepsy patients with partial-onset seizures.
A major new study has confirmed the role played by the prion protein in preventing the onset of epileptic seizures.
US scientists have identified a new treatment approach for a rare yet debilitating form of epilepsy affecting females only.
Epilepsy charities frequently receive enquiries about tonic-clonic seizure alarms, but impartial information about the various ‘makes’ is hard to come by. Epilepsy Research UK, with the support of other epilepsy charities, is conducting independent research into people’s experiences of using different tonic-clonic seizure alarms, with the aim of producing an unbiased information document that will be made readily available to the public. We hope that in the read more
The drug perampanel has been launched in the UK today for the treatment of primary generalised tonic-clonic seizures in adults and adolescents with idiopathic generalised epilepsy.
A new study has shed light on the additional risk of complications and mortality that exist among pregnant women with epilepsy.
Hybrid PET-MRI scans can offer benefits in the evaluation of refractory focal onset epilepsy, according to a new study.
A new study has identified a possible link between sudden unexplained death in childhood and epilepsy in those with a history of febrile seizures.