Below are the most recent news stories about epilepsy from Epilepsy Research UK and from around the world. You can choose different categories from the side bar on the left (for details of grants made prior to 2012, please visit our research portfolio). You can also catch up with Epilepsy Research UK's fundraising and research news in our supporter newsletters.

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New research from Austria has highlighted the potential benefits that the ketogenic diet can offer to children with Dravet syndrome, a serious form of epilepsy. Conducted at the Medical University Vienna, the study aimed to evaluate both the effectiveness and tolerability of the high-fat, low-carb diet in comparison with various AEDs among 32 children who had been treated at the read more

US researchers have identified a common protein that plays a different role than previously thought in controlling certain cell channels that are involved in the development of epilepsy. Conducted by Johns Hopkins Medicine and published in the medical journal Cell, the new study focused on calmodulin, which has been found to make a previously unknown contribution to the opening and read more

Epilepsy patients’ gender can affect their likelihood of experiencing different types of seizure and symptoms, according to a study in Sweden and the US. Published in the journal Epilepsy & Behavior, the research studied seizure semiology data from 1,236 patients with epilepsy to explore differences in seizure types, as well as focal seizure symptoms, between males and females. In patients read more

A new study from India has added to the body of evidence suggesting that saliva could be effectively used in the monitoring of antiepileptic drugs. For this research from the All India Institute of Medical Sciences, the team observed the possible correlation of valproic acid (VPA) concentration between blood samples and saliva in people with epilepsy. A total of 59 read more

A new study from the US has revealed insights into the established link between higher stress levels and an elevated risk of epileptic seizures. Conducted by the Tufts University School of Medicine in Boston, the research identified a potential mechanism underlying changes in neuronal excitability in the hippocampus following chronic stress. Animal test subjects that experienced chronic stress were shown read more

A new single-centre study has added to the body of evidence suggesting that high-fat diets can offer seizure control benefits in epilepsy patients. Conducted by Seattle Children’s Hospital and the University of Washington, the research aimed to determine the efficacy of the modified Atkins diet (MAD) and ketogenic diet (KD) in seizure control within a population of myoclonic-atonic epilepsy (MAE) read more

A new study has suggested that the commonly-prescribed epilepsy therapy lacosamide does not have an adverse effect on sleep patterns. Published in the medical journal Seizure, the multicentre interventional open-label study was conducted in 27 healthy subjects to determine whether lacosamide impacts sleep parameters after 22 days of exposure to therapy. Among the 25 subjects who completed the study, the read more

People with epilepsy are not largely in danger of an increased risk of seizures caused by physical exercise, according to a new study from the University of Lisbon. Published in the medical journal Seizure, the paper examined retrospective and prospective population and animal-based research and determined that in many cases, exercise can actually be beneficial for epilepsy patients, helping them read more

Background Carbamazepine is a widely used anti-epileptic drug, which is usually well tolerated with only mild side effects. In rare cases, however, it can cause a severe, blistering (and sometimes fatal) skin condition, but there is no way of predicting who will have this reaction. In 2011, Epilepsy Research UK awarded Dr Ana Alfirevic and colleagues, at the University of read more

Scientists in the US and Europe have linked several new genes to epileptic encephalopathies. This is the largest collaborative study of its kind to date, and it could lead to the development of new treatments.   Background Epileptic encephalopathies (EEs) are severe, difficult-to-treat childhood epilepsy syndromes, characterised by aggressive seizures (often of multiple types); developmental delay and learning and behavioural read more

A new study has suggested that scans of the frontolimbic brain network could be a useful means of predicting depressive symptoms in temporal lobe epilepsy. Research from the University of California, San Diego has been published in the medical journal Epilepsy Research observing that frontolimbic functional connectivity demonstrates a strong correlation with depressive symptoms. By assessing data from 21 patients read more

Single episodes of juvenile status epilepticus can help to reduce the threshold to adult seizures in various ways, according to new research. Carried out by the University of Ioannina in Greece, the study built on previous findings suggesting that status epilepticus episodes in immature rats can induce a long-term increase in cholinergic excitation, a process that can increase seizure risk. read more

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