The EMA has confirmed a review into the effects of valproate on pregnant women is being carried out.
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Researchers at the University of Bristol have discovered that communication between brain cells is coordinated by a previously unobserved protein, SUMO. Defective neural signalling is associated with a range of disorders, among them epilepsy and autism, meaning their report – which was published in Cell Reports on November 27th – could have huge implications for future research. Cells in the read more
Researchers from the UK and Canada have pioneered a new technique for testing epilepsy drugs.
The Government’s Medicine and Healthcare Products Regulatory Agency (MHRA) has issued new guidance regarding the prescribing and dispensing of anti-epileptic drugs (AEDs). This could have important implications for people with epilepsy. Background The Medicines Act 1968 states that a pharmacist must dispense the exact drug that is written on a prescription. In December 2008, however, the Government announced a plan read more
Researchers in America have developed a piece of software that might one day be used in the development of a seizure prediction device. Background Approximately a third of people with epilepsy don’t respond to anti-epileptic drugs (AEDs) and they continue to experience recurrent seizures. The ability to predict an on-coming seizure would be life-transforming, and in some cases life-saving; and research read more
Researchers in America have made some new discoveries about temporal lobe epilepsy, which could ultimately help neurologists to predict whether epilepsy surgery will be successful. Background Temporal lobe epilepsy (TLE) is the most common type of focal epilepsy, in which seizures arise in the temporal lobes (located on either side of the brain above the ears). Scientists previously thought that read more
People who have adverse reactions to carbamazepine are almost exclusively of Asian descent, according to researchers.
Researchers have discovered how calcium channels selectively filter ions at cell surfaces – a phenomenon sometimes associated with epilepsy.
Taking over-the-counter painkillers could help prevent the memory loss associated with cannabis-derived epilepsy treatments, US scientists believe.
Based on past studies, researchers have concluded that stiripentol is an effective treatment for children with Dravet syndrome.
A recent meta-analysis has provided further evidence that levetiracetam is an effective and well-tolerated adjunctive therapy for several different types of epilepsy. Researchers at Fudan University in Shanghai compared outcomes of multiple randomised-control trials where the drug – prescribed for myoclonic, partial and generalised epilepsies under the NHS – was administered to patients already receiving another antiepileptic therapy. They found read more
The FDA has granted orphan drug designation to Epidiolex, a cannabis-derived treatment for Dravet syndrome.
A team of UK and US scientists have identified the gene responsible for an extremely rare developmental disorder called Warburg Micro syndrome, which leaves patients blind, paralysed and mentally challenged from an early age. They believe that by studying mutations to TBC1D20 – associated with blindness and sterility in mice, but not previously linked to human development – researchers might read more
The FDA has approved a device that electrically stimulates the portions of a patient’s brain thought to cause their epilepsy.
Technologies like video conferencing could make ongoing epilepsy care far more convenient for patients.
Extracts from a common aquatic fern could be used to treat various types of epilepsy, according to a recent study. Researchers at Manipal University in India tested methanolic extracts from marsilea quadrifolia – often grown as a potted plant and considered a weed in some parts of the US – in 48 rats. Two control groups were given established antiepileptic read more
Researchers at the University of Liverpool are attempting to prove that drugs withdrawn due to their side effects can still be administered safely to certain patients. These include carbamazepine, which can be used to treat epilepsy and bipolar disorder, but has also been linked to a life-threatening skin condition called Stevens Johnson Syndrome (SJS). According to the university’s MRC Centre read more
The MHRA has updated advice for doctors and patients regarding AEDs.
Researchers have found that a gene linked to epilepsy plays an important role in the development of the brain.
Scientists in the US have developed an algorithm that uses long-term EEG recordings to predict when an epilepsy patient is about to have a seizure.