Researchers have delivered new insights into the workings of an ion channel in the brain that plays a key role in curbing neuron excitability and preventing seizures.
Below are the most recent news stories about epilepsy from Epilepsy Research UK and from around the world. You can choose different categories from the side bar on the left (for details of grants made prior to 2012, please visit our research portfolio). You can also catch up with Epilepsy Research UK's fundraising and research news in our supporter newsletters.
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Teachers need to be better educated on epilepsy in order to improve general levels of awareness about the condition, according to a new Italian study.
A new study has indicated that childhood-onset epilepsy patients usually experience positive seizure outcomes, though they remain at risk for a number of health conditions.
Patients experiencing behavioural adverse events as a result of using the antiepileptic drug (AED) levetiracetam could benefit from switching to another therapy. This is according to a new study from UCB Pharma and Kentucky One Health, which evaluated the rate of behavioural adverse events in patients receiving levetiracetam who then switched to brivaracetam. A total of 26 patients completed the read more
A new population-based study has offered insights into the prevalence of symptoms of anxiety and depression in school-aged children with active epilepsy. Researchers at a number of UK centres allied with the University of Gothenburg in Sweden saw 69 children with active epilepsy screened using the parental reporting version of the Spence Children’s Anxiety Scale, while 48 utilised the self-reporting read more
A new study has demonstrated the benefits of a UK self-management programme for people with poorly controlled epilepsy.
New research has shed light on the way that childhood epilepsy can have an impact on the development of brain functions, even at early stages of disease. The Korean study, published in the journal BioMed Research International, investigated the relationship between brain structure and neuropsychological status among newly-diagnosed paediatric epilepsy patients who had not yet been treated with antiepileptic drugs read more
A new study has highlighted the potential benefits of oral zinc supplementation in children with intractable epilepsy. Published in the medical journal Functional Neurology, the research from Assiut University in Egypt assessed the impact of supplementation among 45 children aged between three and 12 years who were diagnosed with idiopathic intractable epilepsy. Patients were randomly allocated to two groups, with read more
Sainsbury’s Wolverhampton Interchange Branch have chosen Epilepsy Research UK to be joint beneficiary of their Charity Year after being nominated by staff member Liz Pinto. Thursday 1 October saw a collecting and awareness day, with employee Jack Wilkes donning a dress, dyed hair and having his legs waxed raising £300. Jo Finnerty from ERUK joined the team at Sainsbury’s. Jo says, read more
Vagus nerve stimulation can help to reduce the financial burden associated with secondary care among children and adults with epilepsy, according to a new study.
A new study has demonstrated the potential benefits of levetiracetam in the treatment of epileptic seizures after a liver transplantation. The Taiwanese research, published in the journal Medicine, examined cases of liver failure that required transplantation, the background of seizures, outcomes of seizure control, and the condition of the patient after follow-up at the outpatient department. A total of 15 read more
Patients’ perceptions of their own epilepsy status can have an impact on the relationship between depression and quality of life. In order to assess the relationship, the New York University team looked at 70 patients with epilepsy, who completed questionnaires measuring depression, illness perception and quality of life. According to results published in the medical journal Epilepsia, illness perception statistically read more
A new study has highlighted the discrepancies that often exist between objective measures and subjective perception of cognitive functioning among patients with epilepsy.
A new study has shown the benefits of a digital tool designed to help enhance working memory in children with symptomatic epilepsy.
A new study has highlighted the need to develop new treatment strategies for patients with mutations in the CDKL5 gene causing early-onset epileptic encephalopathy. The international study, published in the European Journal of Paediatric Neurology, aimed to explore the role of different antiepileptic drugs (AEDs) and the ketogenic diet in the treatment of this rare genetic disorder. Researchers evaluated efficacy read more
A new study has indicated that unwitnessed overnight seizures may be a key factor in cases of sudden unexpected death in epilepsy (SUDEP). This supports the findings of previous investigations. Led by the Mater Children’s Hospital in Brisbane, the research aimed to to review population autopsy data on epilepsy-related deaths in Queensland to explore factors associated with autopsy-confirmed sudden unexpected read more
Fellow: Dr Seo-Kyung Chung, Swansea University Cost and duration: £198,520 over 36 months Year awarded: 2011 Background Absence seizures occur in a number of generalised epilepsies, and they are thought to be associated with a defect in the major inhibitory system of the brain, known as the GABA system. GABA is a chemical messenger that is released from read more
A new study comparing generic antiepileptic drugs (AEDs) to their branded counterparts has shown that the generic versions were able to deliver better outcomes. Conducted by Brigham and Women’s Hospital and Harvard Medical School, the study used linked US electronic medical and pharmacy claims data to identify patients who initiated treatment with one of five AEDs – clonazepam, gabapentin, oxcarbazepine, read more
A new pilot study has demonstrated the potential benefits that cognitive rehabilitation training can offer to patients with brain tumour-related epilepsy and cognitive deficits.
Researchers have identified the mechanism by which valproic acid controls epileptic seizures, a discovery that sheds light on underlying factors that cause seizures.