Researchers from Australia and the US have developed an algorithm capable of predicting epileptic seizures with an unprecedented 82 per cent success rate. This is according to the US National Institutes of Health (NIH), which announced the results of the American Epilepsy Society Seizure Detection Challenge last week (January 20th). The competition was launched with the goal of improving seizure read more
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Scientists from the US have announced the discovery of the enzymatic mechanism responsible for preventing Lafora disease, a fatal, neurodegenerative form of epilepsy. Since 1998, it has been known that Lafora disease is caused by mutations in the laforin gene. These mutations prevent the gene from modifying human glycogen and thereby preventing neurodegeneration – a mechanism that has never before read more
UK scientists have discovered a gene that appears to coordinate epileptic activity in the brain, paving the way for new treatment options.
Sleeping in a prone position could increase a person’s risk of SUDEP, according to a new study.
Women of childbearing age need to be better informed of the risks related to the use of sodium valproate during pregnancy. This is according to the UK Medicines and Healthcare Products Regulatory Agency (MHRA), which issued a statement on Wednesday (January 21st) calling for clearer warnings about the side-effects of the common antiepileptic drug. Valproate, which is prescribed to around read more
Brivaracetam, a promising new antiepileptic drug (AED), has been submitted for regulatory approval on both sides of the Atlantic as an adjunctive therapy for patients with partial-onset seizures. The US Food and Drug Administration and the European Medicines Agency will review the findings of an eight-year clinical development programme, which has involved over 3,000 patients and three Phase III studies. read more
Children with refractory epilepsy may be able to improve their life expectancy by opting for surgery rather than continuing medical treatment, according to a new study. Led by Harvard Medical School, the research aimed to quantify life expectancy rates in surgically eligible children with refractory epilepsy, finding that surgery was associated with longer life spans across the range of paediatric read more
A new scientific review has highlighted the benefits that resective surgery can provide for drug-resistant focal epilepsy patients – as well as some of the limitations holding the treatment back from wider acceptance.
A new UK study has highlighted the elevated risk of anxiety and sleep problems among patients with epilepsy.
A new study has shed new light on rates of active convulsive epilepsy, seizure frequency and outcomes of pregnancy among a cohort of pregnant women treated at tertiary hospitals. Published in the medical journal Seizure, the research was led by the University of Maiduguri and saw 7,063 pregnant women attending antenatal care services screened for previous history of epilepsy before read more
Nearly one in five adult epilepsy patients reported attention deficit hyperactivity disorder symptoms, according to a new US study.
A new study has demonstrated the negative impact chronic frontal lobe epilepsy can have on autobiographic memory and mood.
A new study has shed light on some of the factors that affect rates of status epilepticus recurrence among patients.
More needs to be done to prevent hospital crossover among patients in epilepsy in order to minimise the unnecessary use of resources, according to a new study.
A new study has demonstrated the increased risk of stroke among people with adult-onset epilepsy.
A new study has highlighted differences in the brains of children affected by epilepsy and comorbid anxiety issues.
A new study has shed new light on the long-term consequences of West syndrome and the fact that the majority of patients can have at least an acceptable quality of life.
A new study has highlighted potential early clinical predictors of intractable epilepsy in childhood that could be used to guide treatment.
Epilepsy patients with depression may be more likely to find it difficult to adhere to their prescribed treatment regimen, according to a new study.
A new Asian study has further underlined the clinical benefits offered by the antiepileptic drug perampanel, also known as Fycompa.