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26 September 2007
The unpalatability of the foods in the
ketogenic diet is often cited as a reason
for the small number of children treated
with the diet. Researchers from the Kennedy
Krieger Institute in Baltimore, USA, carried
out a study
looking at the food preferences of children
with epilepsy, which was published in the
journal Epilepsy & Behavior in
August.
Some children do extremely well on the
diet, but many drop out. It is so intense
it counts as a medical treatment, and has
to be prescribed, like tablets. It has to
be tailored to a specific child's needs,
which needs accurate calorie and fluid calculation
(so it's a lot of work for parents). It
contains highly fatty foods, such as butter,
cream, mayonnaise, peanut butter, and oils,
in quantities most people find unappealing.
Special oils to boost fat intake are also
available.
Dr Adrianna Amari and her colleagues tested
the food preferences of 29 children with
seizures and compared them to those of 30
children with no history of seizures. The
children were aged between 2 and 17 years.
They also tested whether the children's
parents were good at predicting what sort
of foods the child preferred.
The children in the study were given a
series of choices to make between small
tastes of two foods, one high in fat (for
example, a spoonful of mayonnaise or cream
cheese) and one high in carbohydrate (for
example, a sweet or crisps). They had to
say which one they preferred. The researchers
found that the children with seizures showed
a significantly higher preference for fatty
foods over carbohydrate-high foods, compared
to the children with no history of seizures.
They also found that parents didn't accurately
predict which foods their child preferred.
This interesting finding opens up a number
of possibilities. It may be possible, for
example, to predict a child's response to
the ketogenic diet by how great their preference
for fatty foods is in a test like this.
The underlying reasons for these preferences
also need investigation: is there an underlying
metabolic trigger here?
More about the diet
The ketogenic diet is an effective treatment
for some childhood epilepsies. The diet
contains a very high proportion of fat and
low quantities of carbohydrate. Under these
conditions, the body has to burn fats for
energy rather than burning carbohydrates.
Among the by-products of this process are
chemicals called ketones. High levels of
these in the body reduce seizures, though
exactly how this works is not yet understood.
More
information about the diet can be
found here
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