Can seizures in Angelman syndrome be controlled by gene therapy?
Angelman syndrome is a severe genetic neurological disorder that occurs in children and is most often diagnosed between the ages of 3 and 7 when the clinical symptoms become apparent.
Amongst other symptoms are intellectual and developmental delay. The syndrome is also characterised by epileptic seizures which occur in 90% of cases. There is no known cure and there is no specific therapy available so much treatment has focused on the control of seizures, which are difficult to treat with standard antiepileptic medication.
Now researchers at University of North Carolina School of Medicine have found that gene therapy may prevent the heightened susceptibility to seizures. To read more about this recent research, please use the link here: