Other treatments

How does the ketogenic diet work?

Posted 6 Jul 2017 in Other treatments

A ketogenic diet can help seizure control for some people with drug-resistant epilepsy, but how does it work? Researchers in China have found clues that could potentially help the development of a new epilepsy therapy. Their findings are published in the journal Experimental and Therapeutic Medicine. Background  A ketogenic diet is high in fat, low in carbohydrate and ‘moderate’ in read more

What is Deep Brain Stimulation

Posted 5 Jun 2017 in Brain science; genetics / Other treatments

  Deep Brain Stimulation therapy (DBS) is one of the techniques that a lot of people are talking about, but what does it do? Is it for everyone? And how far along is the research into epilepsy ? Overview DBS is a surgical procedure (an operation).  It involves implanting an electrode into the brain and a  ‘neurostimulator’ into the chest.. read more

Cannabidiol show success in Dravet syndrome

Posted 30 May 2017 in Other treatments

Please note that Epilepsy Research UK does not endorse/promote individual epilepsy treatments or pharmaceutical companies. According to a randomised, double-blind, placebo-controlled trial*, cannabidiol (CBD) reduces seizure frequency in children with Dravet syndrome – a highly complex epilepsy disorder associated with drug-resistant seizures. The findings are published in The New England Journal of Medicine. CBD is a chemical found in the cannabis read more

Improving drug therapies through more effective targeting

New research from the University of Liverpool, published in the Journal of Clinical Investigation, has identified a protein that could help patients with epilepsy respond more positively to drug therapies. There is now increasing body of evidence showing that local inflammation in the brain may be important in preventing control of seizures. Inflammation refers to the process by which the read more

Computer technology increasingly important in study of epilepsy

Posted 5 May 2017 in Brain science; genetics / Other treatments

Two recently published studies show just how important the use of computer technology and modelling have become in the study of epilepsy. A study being carried out at Newcastle University is using a brain model to explore the cause of different epileptic seizure onset patterns. According to the study, at the onset of an epileptic seizure, differing characteristics of brain read more

Research in US shows that cannabis compound may halve seizures for patients with severe epilepsy

Posted 19 Apr 2017 in Other treatments

Researchers from the Ohio State University have found that individuals with Lennox-Gastaut Syndrome (LGS) who took cannabidiol every day for 14 weeks saw the frequency of atonic seizures fall by more than 50 percent. LGS is one of the most severe forms of epilepsy. The condition involves multiple types of seizures, including tonic, atonic, atypical absence, and myoclonic. Atonic seizures, read more

Posterior Cortex Epilepsy Surgery More Likely to Lead to Seizure Freedom When Performed Early

Posted 25 Jan 2017 in Other treatments

Surgery performed in an area of the brain called the posterior cortex is highly effective in controlling seizures and in leading to the discontinuation of antiepileptic drugs (AEDs) in children and adolescents with epilepsy, according to a study published in the scientific journal Epilepsia. Interestingly, the sooner surgery is performed after the diagnosis of epilepsy, the more likely it is read more

Guidelines Comparing Assessment Techniques Prior to Epilepsy Surgery Published

Posted 20 Jan 2017 in Other treatments

The American Academy of Neurology (AAN) has published new guidelines on mapping of the brain prior to epilepsy surgery, following a systematic review of available evidence. The guidelines were published in the academy’s journal Neurology and compared results of functional magnetic resonance imaging (fMRI), a type of scan that assesses brain activity by measuring blood flow, with data obtained from read more

People with Drug Resistant Nonlesional Neocortical Epilepsy Could Benefit from Brain Surgery

Posted 10 Jan 2017 in Other treatments

People with nonlesional neocortical epilepsy could benefit from brain surgery and become seizure-free in the long term according to a study published in the scientific journal JAMA Neurology. Dr Dong Wook Kim and colleagues explored factors that might help select people with nonlesional neocortical epilepsy who are most likely to benefit from surgery. The researchers analysed data from 109 people, aged read more

Cannabidiol May Reduce the Frequency and Severity of Epileptic Seizures

Posted 12 Dec 2016 in Other treatments

Please note that Epilepsy Research UK does not endorse/promote individual epilepsy treatments or pharmaceutical companies. Treatment with cannabidiol (CBD) improves the frequency and severity of seizures in children and adults with epilepsy, according to research presented at the American Epilepsy Society annual meeting in Huston, Texas. The findings are based on an open label,* expanded access clinical trial to test the read more

Modifying AEDs Used by Patients During Vagal Nerve Stimulation Does Not Improve Outcome

Posted 28 Nov 2016 in Other treatments

Changing people’s antiepileptic drugs (AEDs) during vagal nerve stimulation (VNS) does not seem to improve their outcomes, according to a study published in the journal Acta Neurochirurgica. On the basis of this finding, the authors suggest that keeping the same AEDs following the implantation of a VNS device may help optimise its parameters and could improve its effectiveness. In order to read more

Children with Epilepsy on the Ketogenic Diet Should Have their Blood Selenium Levels Closely Monitored

Posted 25 Nov 2016 in Epilepsy in children / Other treatments

An olive oil-based ketogenic-diet leads to a decline in selenium levels in children with drug-resistant epilepsy, according to a study published in the journal of Biological Trace Elements Research. Previous research has shown that low amount of selenium, an element found in trace amounts in the blood that, may increase the risk of seizures. Therefore the levels of selenium in read more

Electrical Brain Stimulation to Treat Drug Resistant Epilepsy in Children

Posted 21 Nov 2016 in Other treatments

The findings of a small study, led by researchers at King’s College London, suggest that electrical stimulation of the brain may be a safe and effective treatment for children with drug-resistant epilepsy, although further research is required. The work is published in the European Journal of Paediatric Neurology. Limited information exists about the effects of brain stimulation in children and, read more

New Antiepileptic Drug Candidate Discovered

Posted 8 Nov 2016 in Other treatments

Please note that Epilepsy Research UK does not endorse/promote individual epilepsy treatments or pharmaceutical companies. Researchers at Elli Lilly and Co., in Indiana, have discovered a new compound that specifically targets neural circuits involved in epilepsy and could potentially be developed into an antiepileptic drug (AED). The findings are published in the leading scientific journal, Nature Medicine. The compound, known as CERC-611, selectively blocks read more

Epilepsy Surgery in the Back of the Brain Can Achieve Excellent Results if Performed Early, Study Suggests

Posted 30 Oct 2016 in Other treatments

Surgery in the back of the brain can attain excellent results if it is conducted early, according to a study published in the scientific journal, Epilepsy and Behavior. Currently this type of surgery is rarely performed, because it is associated with a high number of failures due to the fact that it is extremely difficult to localise the origin from read more

New Compound Could Protect Against the Development of Seizures in Drug-Resistant Epilepsy

Posted 25 Oct 2016 in Other treatments

Please note that Epilepsy Research UK does not endorse/promote individual epilepsy treatments or pharmaceutical companies. A study has shown that huperzine A, a naturally occurring compound often used in traditional Chinese medicine, has a protective effect against experimentally-induced seizures in rodent models of epilepsy. The work is published in the scientific journal, Frontiers in Pharmacology. According to the authors, huperzine A may therefore provide a read more

Epilepsy Surgery in Childhood Does Not Seem to Improve Memory Over Time

Posted 14 Oct 2016 in Other treatments

A new study published in the journal, Epilepsia, suggests that short-term improvements in memory following childhood epilepsy surgery might not be sustained in the long term. These findings may be helpful for physicians, people with epilepsy and their families to better understand the possible outcomes of epilepsy surgery in childhood, and the effects of continuing antiepileptic drug (AED) treatment. For the read more

Surgery Could Improve Psychiatric Problems in Epilepsy

Posted 8 Oct 2016 in Other treatments

Surgery for refractory (drug-resistant) epilepsy may improve psychological changes and psychiatric problems seen in some people with epilepsy, according to a study published in the scientific journal, Epilepsia. First Author Dr Sònia Ramos-Perdigués, at Can Misses Hospital, in Spain, said: “The results of this study suggest that surgery for refractory epilepsy may provide additional benefit in patients with a psychiatric history and read more

Results from Clinical Trial Show Promise for Children with PCDH19 Epilepsy

Posted 1 Oct 2016 in Other treatments

Please note that Epilepsy Research UK does not endorse/promote individual epilepsy treatments or pharmaceutical companies. Marinus Pharmaceuticals has announced the results of a phase two clinical trial evaluating its drug candidate, ganaxolone, for the treatment of PCDH19 epilepsy. They show that ganaxolone was generally safe, well-tolerated and reduced seizure frequency in most participants. In a press release, Dr Michael G. Chez, Paediatric Neurologist at Sutter Medical read more

New Animal Model of Epilepsy Could Help Develop Novel AEDs

Posted 29 Sep 2016 in Other treatments

Researchers at Florida Atlantic University and The Scripps Research Institute,  in the US, have developed a new animal model of epilepsy that will allow the screening of hundreds of thousands of potential antiepileptic compounds. This work is published in the leading scientific journal, Plos One The team, led by Dr Ken Dawson-Scully, genetically modified microscopic worms called C. elegans and were able to chemically or read more

Page 1 of 3012345...102030...Last »

News Updates

Sign up for Research updates

News categories