Other treatments

Epilepsy surgery in childhood does not impact on language in the long term

Posted 22 Aug 2016 in Other treatments

Language skills remain largely unchanged following epilepsy surgery in childhood, according to new research published in the scientific journal Epilepsy and Behaviour. There have been few investigations into brain function after epilepsy surgery in childhood, and these have largely focused on memory and intelligence rather than language. During the current study, researchers at the Hospital for Sick Children, in Toronto, recruited 97 children who read more

‘Sirolimus’ for seizures in tuberous sclerosis complex needs further investigation

Posted 18 Aug 2016 in Other treatments

According to a recent study, published in the journal Neurology, sirolimus* add-on treatment does not significantly reduce seizure frequency in children with tuberous sclerosis complex (TSC) and drug-resistant epilepsy. The authors state, however, that due the small size of the study, larger ones are needed to verify this finding. TSC is a genetic condition that causes tumours to form in different read more

Another cannabidiol trial announced, in Israel

Posted 16 Aug 2016 in Other treatments

Disclaimer: Epilepsy Research UK is completely neutral and is not affiliated with any commercial company, or any particular device/product. The medical company, MMJ PhytoTech Limited, has recently announced that it will begin a new phase two clinical trial by the end of this year to test the effectiveness of its new drug compound, PTL101, in treating children with drug-resistant epilepsy. During the trial, read more

New Technique Could Increase the Success Rate of Epilepsy Surgery

Posted 7 Jul 2016 in Other treatments

Researchers at the University of Exeter have developed an advanced computer model that can identify where in the brain epileptic seizures originate. It can also distinguish, with high accuracy, between the source of a person’s seizures and brain regions that become involved as a result of the seizure starting. This technique could help epilepsy surgeons to identify more accurately the region(s) of read more

FDA approves testing of new surgical device in epilepsy trial

Posted 20 Jun 2016 in Other treatments

Disclaimer: Epilepsy Research UK is completely neutral and is not affiliated with any commercial company, or any particular device/product. Medtronic plc, a medical device company based in Dublin, announced on Friday that the US Food and Drug Administration (FDA) has approved the testing of its Visualase(TM) laser ablation system in a clinical trial. The device will now be used in a read more

Important insights into the link between stress and seizures

Posted 15 Jun 2016 in Other treatments

People with epilepsy frequently report emotional stress/anxiety in the lead-up to a seizure; but although the association between stress and seizures is well recognised, the underlying  mechanisms are still not understood. A research study, published yesterday in the journal Science Signaling, has produced exciting findings that may help the development of new strategies to treat stress-induced epilepsy. Using a rodent model read more

Disappointing result for new epilepsy drug in clinical trial

Posted 14 Jun 2016 in Other treatments

Disclaimer: Epilepsy Research UK is completely neutral and is not affiliated with any pharmaceutical company, or any particular drug compound. Marinus Pharmaceuticals announced yesterday that their drug candidate, ganaxolone, developed for adults with drug-resistant focal onset epilepsy, did not meet the ‘primary endpoint’ (the outcome by which the effectiveness of treatments is evaluated) in a phase three clinical trial. In other read more

New drug being trialled for Dravet syndrome

Posted 10 Jun 2016 in Epilepsy in children / Other treatments

Disclaimer: Epilepsy Research UK is completely neutral and is not affiliated with any pharmaceutical company, or any particular drug compound. The pharmaceutical company, Zogenix, has announced the start of a new clinical trial for a drug compound called ZX008, which it has developed for the treatment of Dravet syndrome. About Dravet syndrome Dravet syndrome is a rare and severe form of read more

Fenfluramine shows long-term efficacy in treating Dravet syndrome

Posted 25 May 2016 in Other treatments

A recent study has shown encouraging evidence for the long-term efficacy of fenfluramine in the treatment of Dravet syndrome, a rare and therapy-resistant epilepsy syndrome. The research, carried out by the University of Antwerp, built on an earlier study of add-on fenfluramine treatment in 12 patients with Dravet syndrome, which was published in 2012. The findings suggested that the drug has a beneficial read more

Fixation on ‘normality’ creates mental issues for people with epilepsy

Posted 25 May 2016 in Living with epilepsy / Other treatments

New UK research has shed light on the potentially negative impact the “burden of normality” can have on the mental outlook of people with epilepsy. Led by St James’ Hospital in Leeds, the study aimed to explore the relationship between psychosocial characteristics prior to epilepsy surgery and quality-of-life outcomes following the operation, with the goal of identifying risk factors for poor read more

Ketogenic diet study shows benefits in refractory childhood epilepsy

Posted 31 Mar 2016 in Other treatments

A new study has demonstrated the benefits of the ketogenic diet in the treatment of children and adolescents with refractory (drug-resistant) epilepsy. Led by Maastricht University, the research aimed to evaluate the efficacy and tolerability of the high-fat, moderate-protein, low-carbohydrate diet, during the first four months of a controlled trial in children with refractory epilepsy aged 1-18 years. After one month’s baseline assessment, enrolled read more

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