Initial diagnosis of focal idiopathic epilepsy in children ‘correct in 90% of cases’

Posted Mar 6 2014 in Statistics; treatment in the UK

In nine out of ten cases, a diagnosis of childhood focal idiopathic epilepsy made after a single seizure does not need to be revised at follow up.

This is according to researchers at the Istituto Giannina Gaslini in Genoa, Italy, who studied 107 patients whose first seizures occurred between the ages of two and 13 years. Each subject was followed up for at least five years.

In 80 children – 74.7 per cent of the cohort – a specific syndrome could be diagnosed after the first seizure.

Specifically, 42.9 per cent of the children were diagnosed as having childhood epilepsy with centro-temporal spikes, while 28.9 per cent were thought to have Panayiotopoulos Syndrome and 2.8 per cent idiopathic childhood occipital epilepsy of Gastaut.

At the end of the follow-up period, the initial diagnosis was confirmed in 72 of 80 children, or 90 per cent of cases.

Of the 25.4 per cent of patients who were unclassified following their first seizures, 40.7 per cent showed no change at follow up, while the remainder had later been diagnosed with other syndromes or atypical forms of epilepsy.

Posted by Steve Long

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