Ketogenic diet ‘effective for patients with Lennox-Gastaut syndrome’
A new study has illustrated the potential benefits that patients with Lennox-Gastaut syndrome (LGS) can experience by adopting a ketogenic diet.
This high-fat, low-carbohydrate, controlled protein diet has been used for many years as a means of controlling epilepsy and can also be helpful to those with LGS, which belongs to a group of epileptic encephalopathies that often prove refractory to antiepileptic drug treatment.
An Argentinean study published in the journal Seizure this month assessed 61 patients who met diagnostic criteria of LGS, with 20 placed on the ketogenic diet and followed for a minimum of 16 months.
After this time had elapsed, it was revealed that 15 of the initial patients remained on the diet, with three patients being seizure-free and a further three seeing a 75 to 99 per cent decrease in seizures. Meanwhile, two had a 50 to 74 per cent drop in seizure frequency and the remaining seven had a decrease of less than 50 per cent.
The researchers therefore concluded: “The KD is an effective and well-tolerated treatment option for patients with LGS, not only for those with cryptogenic, but also for those with structural LGS. The diet should be considered early in the course of this syndrome.”
Posted by Steve Long