A new study published in the scientific journal BMC Pediatrics suggests that the common antiepileptic drugs (AEDs), valproate and oxcarbazepine, may slow growth in children when taken together or on their own. According to the researchers, this could be due to the effect of these drugs on bone metabolism. The team, based at the National Defense Medical Centre in Taiwan, read more
Disclaimer: Epilepsy Research UK is completely neutral and is not affiliated with any pharmaceutical company, or any particular drug compound. The pharmaceutical company, Zogenix, has announced the start of a new clinical trial for a drug compound called ZX008, which it has developed for the treatment of Dravet syndrome. About Dravet syndrome Dravet syndrome is a rare and severe form of read more
New findings suggest that taking topiramate alongside other antiepileptic drugs in pregnancy significantly increases the risk of birth defects.
Research from Japan shows that heart rate variability (HRV – the variation in the time interval between heartbeats) could potentially be used to predict epileptic seizures. Heart rate and rhythm can be easily measured using a wearable sensor, and evidence shows that they are affected by seizure activity. If the ‘predictive value’ of this is confirmed, we will be a read more
Researchers at Yale University have succeeded in developing a ‘representative’ experimental model of focal cortical dysplasia, a common cause of drug-resistant epilepsy. This new tool is likely to be instrumental in improving our understanding of the condition and developing new treatments.
Around one-third of people whose epilepsy fails to respond to the first two treatments eventually go on to achieve seizure freedom, a new study has indicated.
Research suggests that the outcome of epilepsy surgery may depend on a person’s genes.
Systemic family therapy can help to improve signs of anxiety and depression in adolescents with epilepsy, according to a new study.
People with epilepsy treated with vagus nerve stimulation have a reduced risk of sudden unexpected death in epilepsy, according to a new study.
Folic acid could help to prevent autism among the children of women who need to take antiepileptic drugs during pregnancy, according to a new study.
A new study has shed light on the relationship between headaches and mood disturbances in people with epilepsy. Carried out by Sungkyunkwan University School of Medicine, in Seoul, the research examined the nature and prevalence of headaches in people with epilepsy, and explored their correlation with mood problems. The findings are published in the medical journal Epilepsy & Behavior. During the study, a total read more
A new study has highlighted the need for future childhood epilepsy research to be designed with the need to involve the families of children with epilepsy more closely.
Scientists at the US Case Medical Centre, in Ohio, have shown for the first time that sudden unexpected death in epilepsy (SUDEP) can occur even when a seizure has not taken place. This is a highly significant finding, and it suggests that seizure detection devices may not be the most effective tools for prevention. SUDEP is the sudden death of a person with epilepsy for read more
New research has demonstrated the potential benefits that the antiepileptic drug (AED) brivaracetam can provide when administered intravenously. Conducted by the Mid-Atlantic Epilepsy and Sleep Center in Bethesda in the US, the study aimed to examine the feasibility of offering the drug intravenously as an alternative for those unable to benefit from oral therapy. A total of 105 people, aged between 16 read more
According to new research, the diagnosis of seizures can be made easier with the input of people who accompanying patients to doctor’s appointments. The study, conducted by Nelson Mandela Metropolitan University in South Africa, in collaboration with Loughborough University and the University of Sheffield, aimed to evaluate the contributions that companions and witnesses to seizures can make to the diagnostic process. read more
A recent study has shown encouraging evidence for the long-term efficacy of fenfluramine in the treatment of Dravet syndrome, a rare and therapy-resistant epilepsy syndrome. The research, carried out by the University of Antwerp, built on an earlier study of add-on fenfluramine treatment in 12 patients with Dravet syndrome, which was published in 2012. The findings suggested that the drug has a beneficial read more
Prime Minister David Cameron was a very welcome guest at Epilepsy Research UK’s annual supporter reception, where he spoke movingly of his own experience as a parent of a child with epilepsy. The event, held at No 11 Downing Street on Monday 16 May 2016, was hosted by Under Secretary of State for Life Sciences, George Freeman MP, and marked read more
New UK research has shed light on the potentially negative impact the “burden of normality” can have on the mental outlook of people with epilepsy. Led by St James’ Hospital in Leeds, the study aimed to explore the relationship between psychosocial characteristics prior to epilepsy surgery and quality-of-life outcomes following the operation, with the goal of identifying risk factors for poor read more
According to study in Boston, the majority of women with epilepsy who use contraception experience no change in their seizures, but for those who do, the effect seen may depend both on the type of contraception that they are using and the antiepileptic drug (AED) that they are taking. During the study, the largest of its kind to date, the researchers analysed read more
Come along to this public talk, held by the Wales Gene Park, on 23 June 2016. Entry is free, but registration is essential. Click here for more information. Click here for more epilepsy research news.