Our Research Portfolio

Every year we receive between 60 and 70 applications for research into all aspects of epilepsy, and our Scientific Advisory Committee has the task of deciding which of these should be supported. The quality grants that we have awarded in recent years are shown below (most recent first).

Sadly, our funding capacity each year is relatively limited, which means that promising applications have to be rejected. Your donation, no matter how large or small, will help us to fund as much excellent research as possible in the future!

 

Understanding the genetics of mesial temporal lobe epilepsy with hippocampal sclerosis

Grant round winners 2012 Approximately two thirds of people with epilepsy have seizures successfully controlled with anti-epileptic drugs (AEDs). The remaining third do not respond to AEDs (they are said to have refractory epilepsy (RE)) and for these people, other methods of seizure control must be sought. Brain surgery to remove the seizure origin (the area in which seizures originate) read more

Understanding brain networks in temporal lobe epilepsy

Grant round winners 2011 Epileptic disorders can be divided into two groups; those that are focal and those that are generalised. In the past it was thought that generalised epilepsy resulted from an abnormality affecting the whole brain, whilst focal epilepsy involved a defect in just a small area of the brain. However recent evidence suggests that there are, in read more

How do fast brain waves in between seizures come about?

Grant round winners 2011 Approximately two-thirds of people with epilepsy successfully control their seizures with anti-epileptic drugs (AEDs), but for the remaining third, AEDs are not effective (their epilepsy is said to be drug resistant or refractory) and other treatments must be sought. A carefully considered proportion of these people might be eligible for epilepsy surgery (the removal of epileptic read more

Carbogen for children with non-convulsive status epilepticus

Grant round winners 2011 Status epilepticus can be either convulsive (CSE) or non-convulsive (NCSE) and is defined as a seizure lasting 30 minutes or more, or a series of seizures that occur in succession without consciousness being regained in between. CSE is a recognised medical emergency and is very easily detected, however NCSE is a lot rarer and more difficult read more

A better understanding of juvenile myoclonic epilepsy

Grant round winners 2011 Juvenile myoclonic epilepsy (JME) is a common form of generalised epilepsy, which usually presents between the ages of 12 and 18 years and is characterised by myoclonus (involuntary twitching of a muscle/group of muscles) soon after wakening. Most people also experience tonic-clonic seizures and a significant number develop absence seizures. JME has a strong genetic predisposition read more

Investigating the complications associated with Rolandic epilepsy

Grant awarded in 2011 Rolandic epilepsy (RE) is one of the most common paediatric epilepsy syndromes, affecting approximately 10,000 children in the UK, usually between the ages of 3 and 13. Those affected usually suffer either simple partial seizures, often involving the mouth and face, or generalized tonic-clonic seizures. RE is often referred to as benign, as most children ‘outgrow’ read more

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