The balance between excitatory and inhibitory neurons within the brain

Posted Feb 28 2018 in Epilepsy and its causes

Research from the Francis Crick institute has thrown light on the way the right balance between inhibitory and excitatory cells in the brain is created. The disruption of this balance is thought to be critical in conditions such as epilepsy. In simple terms there are two types of neurons in the brain: those which increase activity in other cells (‘excitatory’ neurons) and those which decrease activity (‘inhibitory’ neurons). The balance between the activity of these two types of nerve cell is thought to be implicated in epilepsy, amongst other neurological disorders. This new study from the Francis Crick Institute and King’s College London has shone the light on how the number of inhibitory neurons is determined in the developing cortex of the brain.

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